Kisfaludy Lajos

* Sajógömör, August 30, 1924 – † Budapest, October 30, 1988 / pharmaceutical chemist, corresponding member of the Hungarian Academy of Sciences ; ; He began his school studies in his native village (his father was the director of the ev. school here between 1914–1946), graduated from the ev. high school in Rimaszombat in 1943 and that same year became a student of chemical engineering at the József Nádor University of Technology and Economics in Budapest. He was mobilized at the end of 1944 and became a prisoner of war in Austria. He returned home in the summer of 1945, was resettled in Hungary with his family in 1946 and graduated from the University of Technology as a Hungarian citizen and obtained a chemical engineering degree in 1948. At the university, he was a colleague of the Institute of Organic Chemistry led by Géza Zemplén (Trencsén). He joined the Kőbánya Pharmaceutical Factory in 1956. From 1958 until his death, he was the head of the synthetic laboratory I with the rank of research professor. In 1965–1966, he conducted research at St. John’s University in New York. In 1958, he began to develop the laboratory’s peptide chemistry profile, recognizing the enormous potential of this field in drug research. He was among the first to use protecting groups that prevent the attack of reagents during organic chemical syntheses. Together with his colleagues, he developed a patented process for the production of Suprastin, Seduxen, Eunoctin, Cavinton, etc. Other important research results from a medicinal chemistry and pharmacological perspective include the incorporation of α-aminooxy acids into biologically active peptides, the production of analogues of ACTH, thyrotropin (TRH), pentagastrin and angiotensin, and the development of the so-called “anti-proliferative” compounds in oligopeptides. development of a methodology for rapid peptide synthesis. His industrial research results are protected by nearly 80 patents. He is a multiple recipient of the title of Outstanding Inventor. He shared the State Prize with his colleagues for the development of the synthesis of human hormone (ACTH) that stimulates the function of the adrenal glands. More than 150 scientific papers and book excerpts testify to his life's work. In 1982, the Hungarian Academy of Sciences elected him a corresponding member. ; ; His main works: ; The relationship between theory and practice in peptide chemistry (academic chair holder), 1985.